Starting GLP-1 Treatment: Complete Checklist

Q: What do I need to prepare for my first GLP-1 telehealth consultation?

Before your first GLP-1 telehealth consultation , it’s important to be well-prepared. Start by gathering your medical history , which should include details of any current medications, known allergies, and recent blood test results. Don’t forget to have your NRIC or identification document ready, along with your health insurance information, if it applies. To make the most of your session, jot down any questions or concerns you want to discuss with the doctor. Take time to familiarise yourself with your medication plan as well. This includes understanding the prescribed dosage and learning how to administer injections if they’re part of your treatment. Being prepared helps ensure your consultation is efficient and sets you up to begin your treatment with clarity and confidence.

Thinking about starting GLP-1 treatment for weight loss in Singapore? Here's what you need to know:

GLP-1 Medications: These mimic a natural gut hormone to regulate appetite and blood sugar. Options include semaglutide (Ozempic), liraglutide (Saxenda), and dulaglutide (Trulicity). Only Saxenda is officially approved for weight loss in Singapore, while others may be prescribed off-label.
Eligibility: Typically for those with a BMI ≥30, or ≥27 with weight-related conditions. Adjusted BMI thresholds apply for Asians.
Costs: Treatment starts at S$350/month, but it’s not subsidised by the Medication Assistance Fund (MAF).
Preparation: Gather your medical history, weight metrics, and recent test results before your consultation. Be ready to discuss your health goals and lifestyle habits.
Usage: Follow the prescribed dosing schedule. Injectable medications require proper storage (2–8°C) and administration techniques.
Side Effects: Common issues include nausea, diarrhoea, or constipation, which usually improve over time. Serious symptoms like severe abdominal pain or signs of gallbladder issues require immediate medical attention.
Lifestyle Changes: Combine treatment with a balanced diet, regular exercise, stress management, and quality sleep for the best results.
Monitoring: Track your weight, measurements, and health markers regularly. Schedule follow-ups to adjust your plan as needed.

Trimly offers MOH-approved telehealth consultations with personalised plans, unlimited follow-ups, and medication delivery. Starting GLP-1 treatment is a long-term commitment, but with the right approach, it can support your weight-loss journey effectively.

GLP-1 Treatment Journey: Complete Step-by-Step Checklist for Singapore Patients

Understanding GLP-1 Treatment in Singapore

What Are GLP-1 Medications?

GLP-1 medications are designed to mimic incretin hormones, which naturally help regulate blood sugar and control appetite. These medications, known as GLP-1 receptor agonists (GLP1-RAs), are engineered to work for an extended period. Initially developed to treat type 2 diabetes, they have also proven effective for weight management, supported by extensive clinical research.

In Singapore, commonly prescribed GLP-1 medications include semaglutide (found in Ozempic), liraglutide (found in Saxenda), and dulaglutide (found in Trulicity). Clinical trials have reported significant weight loss outcomes: up to 15.8% over 68 weeks with semaglutide, 6% over 56 weeks with liraglutide, and an impressive 22.5% over 72 weeks with tirzepatide, provided the treatment is properly supervised.

Who Can Use GLP-1 Treatment?

GLP-1 treatment isn’t suitable for everyone. In Singapore, eligibility typically depends on having a body mass index (BMI) of 30 kg/m² or higher, which is classified as obesity. For those with a BMI between 27 and 30 kg/m², treatment may still be an option if they have weight-related conditions like high blood pressure or type 2 diabetes. Given the higher metabolic risks faced by Asian populations, BMI thresholds are adjusted down by 2.5 kg/m².

Certain medical conditions make GLP-1 treatment unsuitable. These include a history of thyroid cancer, pancreatitis, severe kidney disease, or pregnancy. However, under specific conditions, children aged 12 to 17 years weighing more than 60 kg may qualify for this treatment.

Singapore's regulations ensure that these criteria are strictly followed to maximise safety and effectiveness.

Singapore Regulations and Compliance

In Singapore, all GLP-1 medications require a prescription from a licensed doctor. Among these, Saxenda (liraglutide) is the only GLP-1 medication officially approved for weight loss management. While Ozempic (semaglutide) is primarily approved for diabetes treatment, doctors may prescribe it for weight loss under Singapore’s off-label use policy if deemed safe and beneficial.

To ensure safety, it’s crucial to obtain GLP-1 medications from providers licensed by the Ministry of Health (MOH) and compliant with the Health Sciences Authority (HSA). This helps avoid risks such as counterfeit drugs. Doctors typically monitor patients’ progress within three months of starting treatment. If a patient doesn’t achieve at least 5% weight loss after 3–4 months on the maximum tolerated dosage, the treatment is usually discontinued.

It’s important to note that the Ministry of Health’s Medication Assistance Fund (MAF) does not cover liraglutide or semaglutide for weight loss purposes. As a result, patients generally need to pay for treatment out of pocket.

For those seeking GLP-1 treatment, our MOH-approved telehealth service provides licensed consultations and compliant options starting at S$350 per month.

Preparing for Your First Telehealth Consultation

Collect Your Medical Information

Before your telehealth appointment, gather all relevant medical details and health metrics. Your doctor will need a thorough understanding of your medical history, especially if you have conditions like type 2 diabetes, high blood pressure, high cholesterol, fatty liver (MASLD), obstructive sleep apnoea (OSA), polycystic ovary syndrome (PCOS), or knee osteoarthritis linked to weight issues. Be sure to mention any history of pancreatitis, gallstone disease, thyroid cancer, or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2).

Take note of your current weight, BMI, waist circumference, and blood pressure readings. Prepare a list of all medications you’re currently using, including over-the-counter items, supplements, and especially diabetes medications such as insulin or sulfonylureas. If you’ve recently had blood tests - like HbA1c, fasting glucose, lipid panel, liver function tests (LFTs), kidney function (eGFR/renal), or TSH - make sure these results are handy. Additionally, inform your doctor about any known allergies, mood disorders, a history of suicidal attempts, active eating disorders, or stomach and bowel issues like severe gastroparesis or GERD.

Lastly, think about your health and weight goals in advance to ensure your treatment plan is tailored to your needs.

Set Clear Weight and Health Goals

Your focus should extend beyond just the numbers on the scale. Achieving a 5% to 10% reduction in body weight can significantly improve blood sugar levels, cholesterol, and blood pressure. The Health Promotion Board (HPB) suggests aiming for 0.5 to 1 kg per week or 5% to 10% of your body weight over 6 to 12 months.

Set SMART goals that target broader health improvements. These could include better energy levels, improved sleep, enhanced mobility, reduced joint pain, or better mental well-being. Be ready to discuss your current diet, exercise habits, sleep routines, stress levels, and any patterns of emotional eating during your consultation. Keep in mind that a successful plan will require a structured lifestyle approach, including a protein-focused diet, regular resistance training, and strategies to manage sleep and stress.

Finally, ensure you’re practically and financially prepared for this long-term journey.

Check Your Practical and Financial Readiness

Confirm that you have access to a stable internet connection and a device with video capabilities for your consultation. If you’re considering GLP-1 treatment, be aware that it requires a financial commitment. At Trimly, our MOH-approved telehealth service offers both oral and injectable GLP-1 plans, with pricing starting at S$350 per month. Costs vary depending on the dosage and brand.

It’s worth noting that the Ministry of Health's Medication Assistance Fund (MAF) does not cover liraglutide or semaglutide for weight loss. This means the full cost will need to be self-funded. If you’re exploring injectable options, be prepared to discuss your comfort level with self-administering injections, as GLP-1 medications are typically delivered through specific injection devices. Remember, this is a long-term treatment that requires ongoing lifestyle adjustments.

Viral GLP-1 Weight Loss Injection Pen Explained - Halley Explained

Starting GLP-1 Medication Safely

Before diving into tracking your progress, it's essential to ensure your GLP-1 medication is prescribed, administered, and stored correctly.

Verify Your Prescription and Dosing Schedule

When your doctor prescribes a GLP-1 medication, make sure you understand the medication type, starting dose, and the titration plan. These medications usually require a gradual dose increase - starting small and building up slowly - to help your body adjust and minimise any side effects. Double-check whether your treatment is a daily or weekly regimen. For injectable options like semaglutide or tirzepatide, you'll typically begin with a lower dose, which will be increased gradually as per your doctor's instructions. If you're prescribed an oral form, follow the specific timing guidelines provided.

During your consultation, your doctor will measure key health metrics, such as your height and weight, to ensure the prescription fits your health needs. If anything about your dosing schedule or titration plan isn’t clear, don’t hesitate to ask for clarification.

Once you’ve confirmed your prescription details, it’s time to learn how to use and store your medication properly.

Learn How to Use and Store Your Medication

For injectable medications, it's important to follow the correct technique. Rotate injection sites within the same general area, like your upper arms, thighs, or abdomen. Store the medication at a temperature between 2–8°C, keeping it in its original carton to protect it from light. Avoid freezing it. If the medication is removed from refrigeration, follow the manufacturer’s guidelines on how long it can remain at room temperature. Always clean the injection site before use, and avoid injecting into areas with scars or moles. In some cases, taking the medication with or after food may help reduce nausea.

For oral GLP-1 options, take them on an empty stomach with a small amount of water, and wait the recommended time before eating or drinking anything else.

Understanding these steps ensures the medication works effectively and prepares you to handle any side effects.

Handle Common Side Effects

Gastrointestinal side effects like nausea, vomiting, diarrhoea, constipation, and abdominal discomfort are fairly common, especially at the start. These usually improve as your dose increases gradually.

To ease nausea or vomiting, stick with smaller, bland meals and avoid greasy, fried, overly sweet, or spicy foods. Foods with strong smells can also trigger nausea, so steer clear of those. Staying hydrated is key - sip on water or clear liquids throughout the day. Ginger or peppermint tea might also help settle your stomach.

If diarrhoea or constipation becomes an issue, drink plenty of water and slowly increase your fibre intake by including more whole grains, fruits, and vegetables in your diet. Gentle physical activity, like walking, can also support digestion. For injection site reactions, applying a cool compress can reduce swelling and discomfort.

Keep track of any side effects you experience. This will help you and your doctor identify patterns or address any concerns. If side effects persist, worsen, or become severe, consult your doctor without delay.

Monitoring Progress and Adjusting Your Lifestyle

Once you begin GLP-1 treatment, it’s important to keep an eye on your progress right away. Pay attention to how your body reacts and whether your new habits are improving your overall health.

Track Your Results

Weigh yourself once a week, preferably in the morning before eating, and consistently record key measurements like your waist, hips, arms, and thighs. Many people notice weight loss within the first two weeks, with the most noticeable results typically appearing after 12 to 16 weeks of consistent use. For example, users of semaglutide often lose between 5% and 10% of their starting weight within three to six months when combined with lifestyle changes. If you’re using a dual GLP-1/GIP agonist like tirzepatide, the results can be even more impressive - some see weight loss exceeding 15% of their initial body weight over six months.

Even if the scale doesn’t show dramatic changes, you might notice reductions in centimetres, which indicate positive shifts in body composition. It’s also helpful to monitor health indicators like blood pressure, fasting glucose, HbA1c, and cholesterol levels during your regular check-ups.

Additionally, keeping a log of your food intake and physical activity can reveal patterns that might help you fine-tune your approach.

Build Healthy Lifestyle Habits

Tracking progress is only part of the equation - pair it with healthy routines to get the most out of your treatment.

GLP-1 works best when combined with sustainable lifestyle changes. Focus on eating whole, minimally processed foods, prioritising lean proteins and high-fibre carbohydrates. Cutting back on high-fat and high-sugar foods can also help reduce gastrointestinal side effects. To support weight loss, aim for a daily calorie deficit of about 500 kcal.

Incorporate at least 150 minutes of moderate-intensity exercise each week - this breaks down to roughly 30 minutes on five days. Adding strength training twice weekly can help preserve muscle mass and improve insulin sensitivity. If you’re new to exercise, even short 10-minute sessions spread throughout the day can make a difference.

Don’t overlook the importance of sleep and stress management. Poor sleep and chronic stress can increase cortisol levels, which may hinder fat loss and lead to cravings. Practising mindfulness and prioritising quality sleep can not only support your weight-loss goals but also lay the groundwork for long-term health.

Schedule Regular Telehealth Follow-Ups

As you work on building these habits and see progress, staying in regular contact with your doctor is key.

Frequent check-ins with your doctor are essential for evaluating your progress, tweaking your treatment plan, and addressing any concerns. Trimly offers unlimited telehealth follow-ups, giving you convenient access to licensed doctors. These sessions allow your doctor to review your weight trends, health markers, and any side effects, making adjustments to your treatment as necessary.

Use these follow-ups to discuss your progress, challenges, and any changes to your plan. Your doctor can provide continuous guidance on nutrition, exercise, and other habits that support a healthier lifestyle.

Safety Checklist and When to Get Help

After monitoring your progress, it's crucial to ensure your treatment stays safe by keeping these points in mind.

Know the Contraindications and Risks

GLP-1 treatments are unsuitable if you have a personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN2), or a history of pancreatitis. These medications are also not approved for individuals with Type 1 diabetes.

Your doctor will carefully review your medical history to confirm that GLP-1 treatments are safe for you. It's important to provide a complete medical history during your consultation and to follow your doctor's instructions closely. This includes adhering to the gradual dosing schedule, which helps your body adjust safely.

Recognise Warning Symptoms

While common side effects like mild nausea or constipation affect 40% to 60% of patients and generally improve over time, certain symptoms demand immediate medical attention. Seek urgent care if you experience severe abdominal, back, or stomach pain, or if vomiting or diarrhoea makes it hard to stay hydrated. These could signal pancreatitis or lead to dehydration and kidney problems.

Be alert for signs of gallbladder issues, such as pain in the upper right abdomen, fever, or yellowing of the skin or eyes. Additionally, though rare, severe allergic reactions can occur. If you notice difficulty breathing, swelling of the face or throat, or a rapid heartbeat, seek emergency care immediately.

Staying vigilant about these symptoms is just as important as tracking your progress.

Have a Clear Action Plan

For routine concerns, like managing mild side effects or adjusting your dosage, you can contact Trimly through your telehealth portal. Your plan includes unlimited follow-ups, so you can reach out to your doctor anytime without worrying about extra charges.

However, for serious symptoms - such as intense pain, uncontrollable vomiting, signs of dehydration, or allergic reactions - call 995 or head to the nearest Accident & Emergency department right away.

Conclusion: Your GLP-1 Treatment Checklist

Start your GLP-1 treatment journey with confidence by following this checklist. From preparing for your consultation to understanding how to use your medication, staying on track is key. Pair your treatment with a balanced diet, consistent exercise, and stress management to get the best results. These healthy lifestyle changes not only support weight loss but also contribute to better overall health.

With Trimly's telehealth platform, you can stay connected to your doctor for regular check-ins. These sessions help fine-tune your plan and ensure you're building habits that last. Plus, enjoy unlimited follow-ups at no additional cost to support your long-term success.

FAQs

What do I need to prepare for my first GLP-1 telehealth consultation?

Before your first GLP-1 telehealth consultation, it’s important to be well-prepared. Start by gathering your medical history, which should include details of any current medications, known allergies, and recent blood test results. Don’t forget to have your NRIC or identification document ready, along with your health insurance information, if it applies. To make the most of your session, jot down any questions or concerns you want to discuss with the doctor.

Take time to familiarise yourself with your medication plan as well. This includes understanding the prescribed dosage and learning how to administer injections if they’re part of your treatment. Being prepared helps ensure your consultation is efficient and sets you up to begin your treatment with clarity and confidence.

What are some tips for managing common side effects of GLP-1 treatment?

To ease the common side effects of GLP-1 treatment, consider making a few simple changes to your routine. Opt for smaller, lighter meals and steer clear of fatty, spicy, or fried foods, as these can often worsen symptoms. Staying hydrated is key, so drink plenty of water throughout the day. To avoid discomfort, try to finish your meals at least 3–4 hours before lying down.

If you're dealing with nausea, ginger or peppermint might offer some relief. For digestive issues like constipation, slowly increasing your fibre intake could make a difference.

However, if the side effects persist or become more severe, don’t hesitate to reach out to your doctor. They can provide tailored advice to help you manage these challenges while staying committed to your treatment.

What lifestyle adjustments should I make to maximise the benefits of GLP-1 treatment?

To maximise the benefits of your GLP-1 treatment, pairing it with some lifestyle adjustments can make a big difference. Start with a balanced diet that prioritises nutrient-rich foods. Keep an eye on portion sizes and aim to lower your overall calorie intake without compromising on essential nutrients.

Adding regular exercise into your routine is another key step. Aim for 150–300 minutes of moderate-intensity activity each week - this could be brisk walking, cycling, or even dancing. Staying active not only complements your treatment but also boosts overall well-being.

Building healthy habits like mindful eating, sticking to consistent meal schedules, and managing stress can further support your journey. These tweaks, alongside your medication, can help control hunger, boost energy, and encourage steady, long-term weight loss. Make it a point to collaborate with your healthcare provider to tailor these changes to your needs and keep track of your progress.